Answer: Option D
Explanation:
Yeast hybrid and two hybrid screening is a molecular technique which is used to discover and study the protein- protein interaction and protein DNA interaction by testing the physical interaction between two proteins or a single protein in a DNA molecule.
Yeast mutants such as  Schizosaccharomyces pombe and sachromyces cerevisiae have valuable tools for the study of the eukaryotic cell, including DNA repair mechanism and cell cycle control.
Hence, the correct answer is option D