Question

Bob suffers from severe rheumatoid arthritis associated with overproduction of the growth factor RANKL, the receptors for which are present on osteoclasts. Based on this information, ____________ do you predict Bob will have problems regulating.

Answer 1

Answer:

-Increased osteoclast activity

-Increased blood calcium levels

-Increased rate of mineral turnover

Explanation:

Overproduction of RANKL can activate osteoclasts, which cause the bone to fall apart. RANKL and OPG have to be balanced, and this is the aim of therapy for many illnesses in which there is a deficiency of estrogen, such as in this case, rheumatoid arthritis. Other illnesses include bone tumors, osteoporosis, periodontal disease, and more.