Question

Identify the enzyme which catalyses both oxidation as well as phosphorylation events during the same reaction in glycolysis?
a. Pyruvate Kinase
b. Phosphoghycerate kinase
c. Phosphofructokinase 1
d. Glyceraldehyde 3 phosphate dehydrogenase
e. Triose phosphate isomerase

Answer 1

Answer:

D. Glyceraldehyde 3 phosphate dehydrogenase

Explanation:

The enzyme glyceraldehyde 3 phosphate dehydrogenase catalyzes the oxidation of glyceraldehyde 3-phosphate into 1,3-bisphosphoglycerate. This is the first reaction of the payoff phase of glycolysis.

The inorganic phosphate serves as a donor of the phosphate group while NAD+ serves as an oxidizing agent. During the reaction, the aldehyde group of glyceraldehyde 3-phosphate is oxidized into a carboxylic acid anhydride with phosphoric acid.