If we're only counting 5 vowels (A, E, I, O, U) and 20 consonants (everything else, minus T), then there are
[tex]\dbinom52=\dfrac{5!}{2!(5-2)!}=10[/tex]
ways of picking the vowels, and
[tex]\dbinom{20}2=\dfrac{20!}{2!(20-2)!}=190[/tex]
ways of picking the consonants.
We want the word to start with T, and we'll allow any arrangement of the other 4 letters, so that the total number of words is
[tex]4!\dbinom52\dbinom{20}2=\boxed{45,600}[/tex]
Keep in mind that this means words like TRIES and TIRES are treated as different.