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19-08-2019
Chemistry

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A deficiency in thiamine (TPP) will directly decrease the activity of which of the following enzymes? a. Pyruvate carboxylase b. Glucose 6-phosphate dehydrogenase c. Aldolase Bd. Transketolase

Respuesta :

21-08-2019

Answer:

d. Transketolase

Explanation:

Transketolase utilize thiamine diphosphate (ThDP) as cofactor has reduced activity during the thiamine deficiency and results in the tissue damage. The levels of steady-state mRNA of transketolase in human lymphoblasts, fibroblasts and neuroblastoma cells are found to be lower in the thiamine-deficient cultures.

Thus, deficiency in TPP directly decrease the activity of enzyme, transketolase.

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