Question

Part A In order for a reaction to proceed spontaneously from left to right as written ________.
a. ATP must be involved in the reaction
b. A phosphate group must be transferred
c. A common intermediate must be formed
d. The overall free-energy change must be negative

Answer 1

Answer:

d. The overall free-energy change must be negative

Explanation:

For a reaction to be spontaneous, The overall free-energy change must be negative for the reaction.

ΔG of a reaction can be calculated by subtracting the free energy of reactants from the free energy of products.

$\Delta G = G_{products}-G_{reactants}$

Therefore, if a chemical reaction undergoes from a higher value of free energy (Reactants) to a lower value of free energy (Products), then ΔG will be negative in magnitude and the chemical reaction will be spontaneous.

Thus, ATP involved, Phosphate group transferred or a common intermediate must be formed or not, if free energy change is negative, the reaction will be spontaneous.