Answer: B. frequency of alleles in a population
Explanation:
According to the Hardy–Weinberg principle, both the allele and genotype frequencies in a large, random-mating population will remain constant from generation to generation if no mutation, no gene flow, and no selection occur. They are the key to the importance of the Hardy–Weinberg principle, because individual allele frequencies often change in natural populations, with some alleles becoming more common and others decreasing in frequency. Many factors can alter allele frequencies. Only five, however, alter the proportions of homozygotes and heterozygotes enough to produce significant deviations from the proportions predicted by the Hardy–Weinberg principle: mutation, gene flow, nonrandom mating, genetic drift, and selection.
