The work is equal to the line integral of [tex]\vec F[/tex] over each line segment.
Parameterize the paths
The work done by [tex]\vec F[/tex] over each segment (call them [tex]C_1,\ldots,C_4[/tex]) is
[tex]\displaystyle\int_{C_1}\vec F\cdot\mathrm d\vec r_1=\int_0^2\vec0\cdot\vec\imath\,\mathrm dt=0[/tex]
[tex]\displaystyle\int_{C_2}\vec F\cdot\mathrm d\vec r_2=\int_0^1(t^2\,\vec\imath+24t\,\vec\jmath+32t^2\,\vec k)\cdot(4\,\vec\jmath+\vec k)\,\mathrm dt=\int_0^1(96t+32t^2)\,\mathrm dt=\frac{176}3[/tex]
[tex]\displaystyle\int_{C_3}\vec F\cdot\mathrm d\vec r_3=\int_0^2(\vec\imath+(24-12t)\,\vec\jmath+32\,\vec k)\cdot(-\vec\imath)\,\mathrm dr=-\int_0^2\mathrm dt=-2[/tex]
[tex]\displaystyle\int_{C_4}\vec F\cdot\mathrm d\vec r_4=\int_0^1((1-t)^2\,\vec\imath+2(4-4t)^2\,\vec k)\cdot(-4\,\vec\jmath-\vec k)\,\mathrm dt=-2\int_0^1(4-4t)^2\,\mathrm dt=-\frac{32}3[/tex]
Then the total work done by [tex]\vec F[/tex] over the particle's path is 46.