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A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people. Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes.

The alteration of the DNA sequence is called a mutation. The mutation may be harmful and beneficial too.

Mutation can be caused by as follows

  • Physical
  • Chemical
  • Biological

Those substances that cause mutation are called mutagens. Examples of the mutagens are U.V rays, nicotine and gamma rays, and etc

Mutation can be caused by the addition and deletion of the genes in the DNA sequence.

For more information, refer to the link:-

https://brainly.com/question/3523174