Question

Which of the following statements regarding the primary versus the secondary immune response is true?

The antibodies produced in a primary response bind to antigens more efficiently than the antibodies produced in a secondary immune response
A primary response leads to higher levels of antibodies than does a secondary response.
A primary response results when naive lymphocytes are activated, while a secondary response is a result of activating memory cells
A primary response occurs faster than a secondary response

Answer 1

The statement 'a primary response results when naive lymphocytes are activated, while a secondary response is a result of activating memory cells' is TRUE.

• A primary immune response occurs when lymphocytes are activated after the first recognition of the antigenic harmful material (e.g., a specific piece of protein of a virus).

• The naive lymphocytes are withe blood cells, i.e., lymphocytes, which have not yet encountered their antigenic material.

• These cells are activated by antigen-presenting cells, i.e., by dendritic cells and macrophages.

• When memory cells encounter their antigens again, they proliferate and differentiate to produce plasma cells, thereby a secondary (memory) response is generated.

In conclusion, the statement 'a primary response results when naive lymphocytes are activated, while a secondary response is a result of activating memory cells' is TRUE.

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