A woman is heterozygous for a rare dominant autosomal genetic disease, Neurofibromatosis. She marries a normal man (homozygous recessive for Neurofibromatosis), who has Red-Green Color blindness, an X-linked recessive trait. They have children. If the woman is homozygous for normal vision, what is the chance they will have a daughter with color blindness?
A. 100%
B. 50%
C. 0%
D. 25%

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Answer:

Option A

Explanation:

Given -

Man has X-linked recessive trait . Thus its genotype can be represented as

YX'

Woman has normal vision with homozygous genotype i.e "XX"

A cross is carried out between the above two parents thereby producing following offspring -

Y X’

X XY XX’

X XY XX’

Out of four offspring two are boy "XY" which do not have Red-Green Color blindness

While the two daughters "XX' " have Red-Green Color blindness

Thus, all the daughters produced have Red-Green Color blindness. Thus the chance of having a daughter with color blindness is 100 percent

Option A

There are 50% chances that the daughter with color blindness. The correct option is B.

What is autosomal genetic disease?

An autosomal recessive disorder is caused by the inheritance of two changed genes (mutations), one per parent.

These disorders are typically passed down through two carriers. Their health is rarely affected, but the condition is caused by one altered gene (recessive gene) and one unaffected gene (dominant gene).

When only one mutated printed version of a gene causes illness, this is referred to as dominant disease.

The BEST1 gene is passed down to us in two copies, one from our mother and one from our father.

The appearance of one copy of a defective gene causes disease in dominant disease; this defective copy can be inherited from either the mother or the father.

In the given scenario, the father is color blind, so as, one X chromosome in the daughter comes from mother and one from father, so there is 50% chances that the daughter will have color blindness.

Thus, the correct option is B.

For more details regarding autosomal genetic diseases, visit:

https://brainly.com/question/17200072

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