Question

Help me plz!

Question 1:
Offspring with Pompe are cured for life once they receive a dose of the of the GAA enzyme medicine.
True
False

Question 2:
What part of the body is affected by Pompe Disease?
A. Brain and heart
B. Heart and Muscles
C. Muscles and stomach
D. Liver and heart

Question 3:
What part of the cells are involved with Pompe Disease?
A. mitochondria
B. cytoplasm
C. ribosome
D. lysosome

Question 4:
A codon is made up of _____ letters
A. 2
B. 3
C. 4
D. as many as needed to code for the correct amino acid

Question 5:
Where is lots of glycogen stored in the body?
A. Heart muscle
B. Skeletal muscle
C. Respiratory muscles
D. All of the above

Question 6:
Use the following scenario for questions 6-8.
Julia had a sibling who died because of a genetic disease as an infant. Before having children, she and her husband Tobias get genetic testing and counseling. They are unlucky.
For the GAA gene, Julia has one normal allele and one totally non-functional allele. Tobias has one normal allele and one totally non-functional allele.
What is the likelihood that an offspring will have Pompe disease?
A. 0% of having Pompe disease
B. 25% of having Pompe disease
C. 50% of having Pompe disease
D. 75% of having Pompe disease
E. 100%

Question 7:
Use the following scenario for questions 6-8.
Julia had a sibling who died because of a genetic disease as an infant. Before having children, she and her husband Tobias get genetic testing and counseling. They are unlucky.
For the GAA gene, Julia has one normal allele and one totally non-functional allele. Tobias has one normal allele and one totally non-functional allele.
If any of their offspring test positive for Pompe disease, when are symptoms likely to develop (remember, both parents have one non-functioning allele, 0%GAA)?
A. Before the age of nine months
B. Anytime during adolescence up through middle adulthood.

Question 8:
Use the following scenario for questions 6-8.
Julia had a sibling who died because of a genetic disease as an infant. Before having children, she and her husband Tobias get genetic testing and counseling. They are unlucky.
For the GAA gene, Julia has one normal allele and one totally non-functional allele. Tobias has one normal allele and one totally non-functional allele.
Imagine you are their genetic counselor. Explain to the parents, what causes the disease and explain how it affects the body and how the treatment for Pompe will work.
Use this checklist to make sure your answer is complete:
How is the DNA of an offspring with Pompe different than the DNA of somewhat without the disease?
What function is being disrupted at the cellular level ?
Why does having this disease lead to death (what happens to the body)?
What is the treatment that is used to help Pompe patients?
How does it "fix" the problem?
Are offspring with Pompe cured for life once they receive a dose of the medicine? Explain why or why not.

Answer 1

Question 1 :

False.

It isn't 100% curable.

Question 2 :

The heart and muscles are parts of the body affected by Pompe Disease.

So the correct answer is B.

Question 3 :

lysosomes are part of the cells involved with Pompe Disease.

So the correct answer is D.

Question 4 :

A codon is made up of 3 letters.

So the correct answer is B.

Question 5 :

Lots of glycogen is stored in the skeletal muscle.

So the correct answer is B.

Honestly I'm not sure about the last three. I wouldn't want to give you false answers.

Hope I've been at least of some help (:,

Davinia.

Answer 2

The explanations are mentionned in the attached file.

1. The right answer is False.

2. The right answer is B.

3. The right answer is D.

4. The right answer is 3 letters.

5. The right answer is B.

6. The right answer is 25%.

7. The right answer is A.

The answers for question 8 according to the checklist are in the attached file too.