Which issue played the GREATEST role in increasing tensions between South Carolina and Great Britain in the years leading up to the American Revolution? Question 4 options: The colonists were upset because Great Britain imposed taxes on the colonists to pay for the French and Indian War. The colonists were upset because Parliament passed legislation to end the importation of slaves into the American colonies. The colonists were upset because of King George's decision to keep the Backcountry region closed to new settlement to prevent conflicts with the Native Americans The colonists were upset because Great Britain had supported an armed uprising of the Cherokee and Catawba Indians against colonial settlements along the frontier.

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The correct answer is "The colonists were upset because Great Britain had supported and armed uprising of the Cherokee and Catawba Indians against colonial settlements along the frontier."

A big part of the Cherokee tribe allied with Great Britain who had convinced them to fight on their side. Many of the bloodiest battles the Carolinians took up, ended up being against cherokees who got out of hand and started not only attacking Patriots but causing havoc all over the frontier. In the end, South Carolina led a successful campaign against the indians and regained control of the region.

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