The right option is; Culture shock.
Susan was feeling uncomfortable and disoriented because she was experiencing culture shock.
Culture shock is a feeling an individual may experience when one relocates to a different cultural or social environment. Culture shock usually occurs when an individual is in a foreign environment and it involves unfamiliarity with social norms, new foods, culture etc. Common situations such as technology gap, language barrier, and boredom can also be experienced. Culture shock mainly undergoes four different stages which are; honeymoon, frustration, adjustment and acceptance.