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A pandemic is the worldwide spread of a new disease. An influenza pandemic occurs when a new influenza virus emerges and spreads around the world, and most people do not have immunity. Viruses that have caused past pandemics typically originated from animal influenza viruses. For example, in 2003, the severe acute respiratory syndrome (SARS) epidemic took the lives of nearly 800 people worldwide. A pandemic is a global disease outbreak. HIV/AIDS is an example of one of the most destructive global pandemics in history. Spanish influenza killed 40-50 million people in 1918.

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A pandemic disease spreads from country to country. An example of this is the Black Death which spread across the world and killed millions of people in the 14th and 15th centuries.

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