E = mc^2 is an equation derived by physicist Albert Einstein. It means "energy equals mass multiplied by speed of light squared (or multiplied by itself)." It expresses the fact that both mass and energy are the same physical entity and can be changed into each other. In fact, energy and mass are different forms of the same thing. In the said equation, the mass (represented by m) multiplied to the velocity of light squared (c^2) is equivalent to kinetic energy (e).
The E = mc^2 equation explains how every star (including our Sun) works by nuclear fusion (atoms fusing together while some of their mass is converted into energy), the atomic energy produced by nuclear power plants and atomic energy released by atomic bombs, and how matter can be destroyed and converted to energy and energy can be converted back to mass.