I believe the answer is:
- Asymmetery,
the moles that indicate melanoma tend to have uneven sides
- Border irregularity,
Harmless mole tend to be closer to a perect circle compared to melanoma moles
- Color,
Melanoma moles tend to be significantly darker compared to normal moles
- Diameter,
Compared to harmless moles, melanoma moles tend to be larger in size
- Evolving
The size of melanoma moles would keep growing over the years while harmless moles tend to stay the same.