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The difference between ribose and deoxyribose is that in ribose the second carbon atom carries hydroxyl group while in deoxyribose, the second carbon atom contains only hydrogen atom. Ribose and Deoxyribose make up the backbone of RNA and DNA respectively.
A feature which distinguishes ribose from deoxyribose is, the absence of an OH at the 2' carbon.
In the ribose the second carbon atom contains hydrogen atom only. Ribose is termed as the carbohydrate.
It is a simple sugar which has linear form H-. It is a monosaccharide which contains five carbon atoms.
Deoxyribose is being derived from DNA and it differs from ribose by having hydrogen atom instead of hydroxyl group which functions as a RNA splicing.