The optimal pH for enzyme Q is 6.4 and the optimal temperature is 45 degrees Celsius. Enzyme Q is in a solution that has a pH of 7 and a temperature of 35 degrees Celsius. Which of the following would increase the rate of the reaction that is catalyzed by enzyme Q the most?
a. decreasing the pH to 6.4 and not changing the temperature
b. increasing the pH to 7.4 and decreasing the temperature to 28 degrees
c. increasing the pH to 7.4 and increasing the temperature to 45 degrees
d. decreasing the pH to 6.4 and increasing the temperature to 45 degrees
e. decreasing the pH to 6.4 and decreasing the temperature to 28 degrees