A patient is 67 years old with HbA1c test result 9% and has diabetes mellitus. His cardiovascular risk was >15%. His renal health screen showed an eGFR 90mL/min/1.73m² with microalbuminuria of 3.5mg/mol. Decreased dorsalis pedis and posterior tibialis pulses in both legs. Medication: Ramipril 5mg daily. Demonstrate understanding of the physiological and pathophysiological processes related to the patient presentation. Articulate the expected evidence of effectiveness of therapy. Mention mechanism of action, aim of therapy for this medication specific to the patient using guidelines

a) Physiological processes
b) Pathophysiological processes
c) Evidence of effectiveness
d) Ramipril mechanism of action