List common side effects of opioids. What is the most serious and potentially fatal side effect? By what mechanism does this side effect occur? Which patients are the highest risk? 10. How do you deprescribe long-term opiates? 11. What is an example of an opioid antagonist and for what purpose is it used?
a) Constipation; Respiratory depression; Depresses gastrointestinal motility; Elderly patients.
b) Nausea; Hypertension; Stimulates the chemoreceptor trigger zone; Children.
c) Diarrhea; Bradycardia; Blocks mu-opioid receptors; Pregnant women.
d) Sedation; Seizures; Reduces CNS excitability; Patients with a history of addiction.
