To calculate the rate of mutation by sequencing of a single gene, researchers Ballin & Cascalho assumed that only one copy of the gene of interest (gp140) was being expressed in each clone analyzed. They found that the rate of mutation was 8.1 × 10⁻⁵ mut/bp per cell generation. If we were to assume that we have two alleles in this population and their initial frequencies are b1 = 0.3 and b2 = 0.7. Calculate the frequencies of these two alleles in the next generation given the mutation rate (assume that the mutation rate adds to the B1 allele)
