Which of the following antibiotic combinations, given orally, would offer the best overall coverage for gram-positive, gram-negative, and anaerobic infections?
1) Penicillin and ofloxacin
2) Erythromycin and trimethoprim/sulfamethoxazole
3) Clindamycin and ciprofloxacin
4) Metronidazole and oxacillin