Hairy cell leukemia is a cancer of the white blood cells that responds to treatment with drugs that inhibit dna synthesis. A mutation in the braf gene, designated braf v600e, is associated with hairy cell leukemia. Braf v600e differs from the nonmutant braf gene in a single base pair. Imagine that this change to the single base-pair added a hae iii restriction site indicated by the arrow on the gene below. You decide to identify hairy cell leukemia with pcr and the restriction enzyme hae iii.
