: Metabolism is the broad term used to describe all biochemical reactions occurring in the body Metabolism involves building and breaking down molecules to store or release energy called ATP The most important hormone in maintaining metabolism is thyroi d 12 In this experiment you will investigate the effects of various treatments and hormones on the metabolism of the three rats. Metabolism is measured by O usage Experimental Treatments 1) Normal rat 2) Thyroidectomized rat - rat with thyroid gland removed 3) Hypophysectomized rat - rat with pituitary gland removed Effects of Experimental Treatments on Metabolism Metabolic Rate (ml Oz/kg/hr) Rat # NOT Normal Rats Thyroidectomized Hypophysectomized Ratsid Rats pituitar Rat #2 Rat #3 Baseline metabolic rate = 4750 metabolic rate = 2440 metabolic rate=2450 Rat #4 Rat #5 Rat #6 + Thyroxine metabolic rate = 5220 metabolic rate=4730 metabolic rate = 4720 Rat#7 Rat #8 Rat #9 + TSH metabolic rate = 5195 metabolic rate=2450 metabolic rate=4710 Rat #10 Rat #11 Rat #12 + Propylthiouracil metabolic rate = 2890 metabolic rate=2430 metabolic rate = 2450 Note: Metabolic rate changes smaller than 100 are due to differences in rat size and behavior. Not a change in overall metabolic rate. Questions 1) How is metabolic rate measured in this experiment? Why does it correlate to metabolism? BMR is measured by the different Hormones 2) What hormone(s) would be missing from the blood of the thyroidectomized animal? ! T3 T4
