to reduce brain swelling by pulling water out of brain cells, a substance can be injected intravenously to increase the osmotic pressure of interstital fluid. which of the following properties can this substance NOT have to be effective?

a. permeable to capillary endothelium

b. permeable to brain plasma membranes

c. nontoxic to neurons

d. impermeable to brain plasma membranes

e. soluble in water