Which of the following statements regarding signal sequences is NOT true? Proteins modified with a mannose-6-phosphate localize exclusively to the lysosome. O The KDEL receptor contains a C-terminal Lys-Lys-X-X sequence. The di-arginine sorting sequence can be located anywhere in the cytoplasmic domain of an ER-resident protein. O A protein with a KDEL sequence localizes to the ER via COPI retrieval.
