DNA to Protein
7. A gene has a base sequence of GTC. Due to a mutation, the base sequence changes to GTG. Answer the following questions using the codon table below.
a) What are the bases of mRNA coded for by this section of DNA, before the mutation? (1 point)
b) What are the bases of mRNA coded for by this section of DNA, after the mutation? (1 point)
c) What amino acid is coded for by this sequence before the mutation? (1 point)
d) What amino acid is coded for by this sequence after the mutation? (1 point)
e) Is this is a silent mutation or a missense mutation? Explain. (1 point)
g) If the strand of DNA with the sequence GTA mutated to GTG, would this be a silent or missense mutation? (1 point)
h) If the strand of DNA with the sequence TTA mutated to TTG, would this be a silent or missense mutation? (1 point)
i) If the strand of DNA with the sequence TGA mutated to GGA, would this be a silent or missense mutation? (1 point)
8. A gene has a base sequence that begins with TAA CTA TGA CGT CG. Answer the following questions using the codon table from question 7.
a) What RNA sequence would be produced during transcription? (1 point)
b) What are the first four amino acids coded by this sequence? (1 point)
c) The gene has a frameshift mutation, where the fifth base in the sequence is deleted. Write the new DNA base sequence. (1 point)
d) What is the new RNA sequence? (1 point)
e) What are the first three amino acids coded by this new mutated sequence? (1 point)
f) How does the correct amino acid sequence compare to the mutated sequence? (1 point)
