T cell differentiation Select one: a. is determined by the type of peptide presented by the MHC class I or class II molecules. b. that results in a TH1 response requires the secretion of IL-12 by cytotoxic T cells. c. that occurs in response to multicellular parasites leads to the production of high levels of IgG antibodies. d. is not dependent on the expression of particular transcription factors. e. due to co-stimulation by ICOS results in the activation of B cells.