The common local effects of an expanding tumor mass include: 1. obstruction of a tube or duct. 2. anemia and weight loss. 3. cell necrosis and ulceration. 4. tumor markers in the circulation. a. 1 and 2. b. 1 and 3. c. 2 and 4. d. 3 and 4.The common local effects of an expanding tumor mass include: 1. obstruction of a tube or duct. 2. anemia and weight loss. 3. cell necrosis and ulceration. 4. tumor markers in the circulation. a. 1 and 2. b. 1 and 3. c. 2 and 4. d. 3 and 4.The common local effects of an expanding tumor mass include: 1. obstruction of a tube or duct. 2. anemia and weight loss. 3. cell necrosis and ulceration. 4. tumor markers in the circulation. a. 1 and 2. b. 1 and 3. c. 2 and 4. d. 3 and 4.