The release of lytic granules from cytotoxic T cells is aimed specifically at infected target cells while preserving the integrity of neighboring, uninfected cells. This is best explained by the observation that Select one: a. only target cells bearing appropriate peptide:MHC class I complexes are susceptible to necrosis. b. redistribution of lytic granules in the T cell delivers them to confined areas on the target cell in contact with the T cell. c. regulatory T cells deliver survival signals to uninfected neighboring cells that renders them resistant to cytotoxins. d. the amount of cytotoxins in a given cytotoxic T cell is so limited that only the cell closest to the T cell will succumb to the effects of perforin and granzyme. e. uninfected cells are highly resistant to the effects of cytotoxins.
