You have a patient with extensive birth defects that affect the kidney anatomy. Nevertheless, she does have some kidney function. One thing you've noticed in her labs is extremely low renin secretion. Which of the following anatomical locations is likely to exhibit abnormal development?
A. The proximal tubule
B. The glomerular capillaries
C. The efferent arteriole
D. The ascending limb of the loop of Henle
E. The juxtaglomerular apparatus