Recall the role of Tropomyosin (TM) in regulating skeletal muscle contraction. Will a mutant form of TM that is unable to bind the Troponin complex function in a dominant-negative fashion to affect muscle contraction? No, because the mutant TM and Troponin will bind to actin filaments independently No, because the mutant TM cannot bind to the actin filaments No, because the mutant TM will be displaced easily from the actin filaments Yes, because the mutant TM can never be displaced from the actin filaments Yes, because the mutant TM can still bind strongly to calcium ions
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