Compare and contrast the two approaches to genome sequencing (whole-genome shotgun sequencing and clone-by-clone sequencing). Drag the appropriate items to their respective bins. Reset Help the genomic DNA is first broken into fragments and sequenced sequences are assembled into contigs based on sequence overlaps require piecing together overlapping sequences prior construction of a physical map seek to completely cover an organism's entire genome a chromosome is first broken into overlapping fragments Whole-genome shotgun sequencing Clone-by-clone sequencing Both
