Charles II was the last Habsburg King of Spain whose ineffectual reign was in large part due to extensive physical, intellectual and emotional problems. Charles II was born November 6,1661 to Philip IV and Mariana of Austria, who was the niece of Philip IV. Philip IV was the son of Philip III and Margaret of Austria. Mariana of Austria was the daughter of Maria Anna of Austria, Philip IV's sister, and the Holy Roman Emperor, Ferdinand III. Assuming no additional inbreeding in this family, what is the inbreeding coefficient for Charles II? A. 0.125 B. 0.25 C. 0.375 D. 0.5 E. 0.625