Which one of the following occurs during the conversion of pyruvate to glucose during gluconeogenesis?
(A) Biotin is required as a cofactor.
(B) The carbon of CO2, added in one reaction,
appears in the final product.
(C) Energy is utilized only in the form of GTP.
(D) All of the reactions occur in the cytosol.
(E) All of the reactions occur in the mitochondrion.