One of the key considerations when developing antibiotics is targeting bacteria without harming the infected individual. Protein
synthesis in bacteria and eukaryotes are different enough that this is a good target for antibiotics that inhibit translation
machinery. In fact, antibiotics that inhibit bacterial translation can do so in different ways.
Select the specific mechanisms by which certain antibiotics interfere with translation.
binds to the 50s ribosomal subunit
binds to the ribosome and blocks subsequent translation
supercoiled DNA
relaxes
interferes with gyrase, which refs
inhibits cell structural integrity by interfering with peptidoglycan synthesis