Which of the following is true regarding crystalline proteins?

A) Many crystallized enzyme proteins remain catalytically active
B) The diffractive pattern observed during X-ray exposure to the crystal can be used to calculate the electron density map of the crystalline protein.
C) The larger region indicating electron density with in the electron density map, the more accurate the structure determination.
D) A and B are true. E) A, B, and C are true.